Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22366387 | 0.86 | S1PR5 (0.42) | S1PR5HPGDTSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL22319819 | 0.85 | S1PR5 (0.47) | S1PR5HPGDTSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL18584701 | 0.84 | ABHD6 (0.43) | S1PR5HPGDTSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL16269608 | 0.83 | UCHL1 (0.49) | S1PR5ABHD6 | |
| SCHEMBL28901639 | 0.83 | ABHD6 (0.41) | S1PR5HPGDTSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL16268894 | 0.83 | S1PR5 (0.40) | S1PR5HPGDTSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL22319890 | 0.83 | S1PR5 (0.41) | S1PR5HPGDTSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL16269635 | 0.78 | S1PR5 (0.47) | S1PR5TBXA2RHPGDHSD17B10HDAC8 | |
| SCHEMBL5777006 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2ABHD6NOTUMTAAR1HDAC8 | |
| SCHEMBL6279147 | 0.76 | ALDH1A1 (0.44) | S1PR5SMN1; SMN2ABHD6TAAR1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105263924-B | Cxcr7 receptor modulators | 爱杜西亚制药有限公司 | 2018-10-19 | — | — | CN | disclosed |