Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | BPTF | Q12830 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28796833 | 0.80 | HPGD (0.36) | MAPK1HPGDRECQLNPSR1ALDH1A1 | |
| SCHEMBL29035272 | 0.76 | BPTF (0.41) | HPGDALDH1A1BPTF | |
| SCHEMBL31198110 | 0.70 | MEN1 (0.43) | HPGDALDH1A1 | |
| SCHEMBL5774668 | 0.70 | MEN1 (0.43) | HPGDALDH1A1 | |
| SCHEMBL30772837 | 0.70 | ALDH1A1 (0.49) | HPGDNPSR1ALDH1A1ADORA1 | |
| SCHEMBL28691048 | 0.70 | HPGD (0.37) | MAPK1HPGDRECQLNPSR1ALDH1A1 | |
| SCHEMBL28796886 | 0.69 | BPTF (0.33) | HPGDALDH1A1BPTF | |
| SCHEMBL28449501 | 0.69 | KCNQ2 (0.44) | HPGDRECQLNPSR1ALDH1A1 | |
| SCHEMBL22982202 | 0.69 | BTK (0.37) | HPGDALDH1A1 | |
| SCHEMBL28931023 | 0.69 | NOTUM (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279370-A | Compounds for targeted degradation of BRD9 | C4医药公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-114380799-A | COT modulators and methods of use thereof | 吉利德科学公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-109879859-B | COT modulators and methods of use thereof | 吉利德科学公司 | 2022-01-25 | — | — | CN | disclosed |