SCHEMBL29035272

SCHEMBL29035272

N#Cc1csc2c1CCN(C(=O)O)C2

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BPTF Q12830 1/20 0.41
MAPT P10636 4/20 0.37
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
ALDH1A1 P00352 3/20 0.37
GAA P10253 2/20 0.37
HPGD P15428 2/20 0.37
ALOX15 P16050 1/20 0.37
HSD17B10 Q99714 1/20 0.37
KDM4E B2RXH2 2/20 0.37
GRM1 Q13255 8/20 0.37
TAS1R3 Q7RTX0 1/20 0.34
TAS1R1 Q7RTX1 1/20 0.34
TAS1R2 Q8TE23 1/20 0.34
DAO P14920 1/20 0.33
NOTUM Q6P988 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25363322 0.80 ADORA1 (0.51) MAPTGAAKDM4E
SCHEMBL28796833 0.80 HPGD (0.36) BPTFMAPTMEN1KMT2AALDH1A1
SCHEMBL28901663 0.76 MAPK1 (0.34) BPTFALDH1A1HPGD
SCHEMBL4035961 0.71 BPTF (0.78) BPTFMAPTMEN1KMT2AALDH1A1
SCHEMBL5600099 0.70 KMT2A (0.45) MAPTMEN1KMT2AALDH1A1ALOX15
SCHEMBL4788512 0.70 TAS1R3 (0.51) MAPTMEN1KMT2AALDH1A1TAS1R3
SCHEMBL28691048 0.70 HPGD (0.37) BPTFMAPTMEN1KMT2AALDH1A1
SCHEMBL30772837 0.70 ALDH1A1 (0.49) MAPTMEN1KMT2AALDH1A1GAA
SCHEMBL939185 0.69 RXFP1 (0.43) BPTFMAPTMEN1KMT2AALDH1A1
SCHEMBL28796886 0.69 BPTF (0.33) BPTFMEN1KMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116437913-A Pharmaceutical compounds for treating complement-mediated disorders 艾其林医药公司 2023-07-14 CN disclosed