Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MPL | P40238 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290136 | 0.74 | SMN1; SMN2 (0.50) | SCN9AHDAC6POLBNPSR1CYP2C9 | |
| SCHEMBL25093294 | 0.71 | APP (0.47) | APPSCN9AHSD11B1S1PR1HDAC6 | |
| SCHEMBL289570 | 0.71 | ALDH1A1 (0.55) | SCN9ACYP2C9ALDH1A1 | |
| SCHEMBL13064837 | 0.69 | ALDH1A1 (0.46) | SCN9AALDH1A1 | |
| SCHEMBL4035686 | 0.66 | HDAC6 (0.42) | APPSCN9AHSD11B1HDAC6POLB | |
| SCHEMBL289855 | 0.66 | MAPT (0.44) | POLBNPSR1ALDH1A1L3MBTL1ABL1 | |
| SCHEMBL7701143 | 0.65 | ALDH1A1 (0.50) | SCN9AHSD11B1S1PR1POLBNPSR1 | |
| SCHEMBL900653 | 0.65 | F2RL3 (0.47) | SCN9AHSD11B1S1PR1CYP2C9ALDH1A1 | |
| SCHEMBL16546583 | 0.65 | S1PR1 (0.37) | APPSCN9AHSD11B1S1PR1HDAC6 | |
| SCHEMBL16546540 | 0.64 | APP (0.37) | APPSCN9AHSD11B1HDAC6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |