Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.35 |
| ▸ | KDM4A | O75164 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.35 |
| ▸ | TET3 | O43151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954549 | 0.85 | TET2 (0.46) | TSHRTET2KDM4AKDM4CKDM2A | |
| SCHEMBL2888407 | 0.79 | L3MBTL1 (0.37) | TSHRKMT2ALMNACYP1A2 | |
| Malonic Acid SCHEMBL15654125 | 0.71 | LDHA (0.45) | TSHRKMT2AMAPTABCC4HSD17B10 | |
| SCHEMBL9176186 | 0.71 | TET2 (0.42) | CYP2D6NFKB1TET2KDM4AKDM4C | |
| SCHEMBL12617396 | 0.70 | ACE (0.40) | TSHRTET2KDM4AKDM4CKDM2A | |
| Bicarbonate SCHEMBL9715828 | 0.70 | — | — | |
| SCHEMBL27995352 | 0.67 | BLM (0.41) | BLMKMT2AMAPTLMNACYP1A2 | |
| SCHEMBL12227361 | 0.66 | ANPEP (0.43) | KMT2AMAPTABCC4LMNAGABRA1 | |
| Acetic Acid SCHEMBL31249677 | 0.66 | — | — | |
| SCHEMBL27634689 | 0.64 | MEN1 (0.46) | TSHRSLC6A2SLC6A4BLMSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2128149-B1 | Tetrahydrofuran compound, liquid crystal composition and liquid crystal display device containing the liquid crystal composition | JNC CORP (JP) | 2013-07-24 | — | — | EP | disclosed |
| EP-1798228-B1 | TETRAHYDROPYRAN COMPOUNDS, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAYS CONTAINING THE COMPOSITIONS | JNC CORP (JP) | 2012-11-14 | — | — | EP | disclosed |
| US-7842357-B2 | Tetrahydropyran compound, liquid crystal, composition and liquid crystal display device containing the liquid crystal composition | CHISSO CORPORATION (JP) | 2010-11-30 | — | — | US | disclosed |
| EP-2128149-A1 | Tetrahydrofuran compound, liquid crystal composition and liquid crystal display device containing the liquid crystal composition | Chisso Corporation (JP) | 2009-12-02 | — | — | EP | disclosed |
| EP-1798228-A1 | TETRAHYDROPYRAN COMPOUNDS, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAYS CONTAINING THE COMPOSITIONS | CHISSO CORPORATION (JP) | 2007-06-20 | — | — | EP | disclosed |
| US-20060071194-A1 | Tetrahydrofuran compound, liquid crystal, composition and liquid crystal display device containing the liquid crystal composition | JNC PETROCHEMICAL CORPORATION (JP) | 2006-04-06 | — | — | US | disclosed |