Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.57 |
| ▸ | ALB | P02768 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | DRD1 | P21728 | 1/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.51 |
| ▸ | RAB9A | P51151 | 9/20 | 0.51 |
| ▸ | NPC1 | O15118 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | TP53 | P04637 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29394557 | 0.86 | TTR (0.52) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL10271390 | 0.84 | NPC1 (0.64) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL15014132 | 0.82 | NPC1 (0.57) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL10272058 | 0.81 | ALDH1A1 (0.56) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL22946076 | 0.80 | SMN1; SMN2 (0.68) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL19380064 | 0.79 | NPC1 (0.64) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL10271557 | 0.79 | MAPT (0.58) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL3900968 | 0.78 | NPC1 (0.57) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL3900972 | 0.78 | NPC1 (0.57) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL9305682 | 0.78 | RAB9A (0.46) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115286591-B | Synthesis method of drug Tafamidis | 湖南第一师范学院 | 2023-10-20 | — | — | CN | disclosed |
| CN-115286591-A | Synthetic method of drug Tafamidis | 湖南第一师范学院 | 2022-11-04 | — | — | CN | disclosed |