Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartic Acid SCHEMBL27200583 | 0.93 | GRIK1 (0.42) | GSRGRIK1GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL28871434 | 0.93 | GSR (0.47) | GSRGRIK1GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL10954257 | 0.82 | GRIK1 (0.46) | GSRGRIK1GRIK2GRM1GRM2 | |
| D-Aspartate SCHEMBL30290726 | 0.82 | GRIK1 (0.46) | GSRGRIK1GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL10954254 | 0.82 | GRIK1 (0.46) | GSRGRIK1GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL31555109 | 0.78 | GSR (0.64) | GSRGRIK1GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL27966204 | 0.78 | GRIK1 (0.50) | GSRGRIK1GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL14742381 | 0.78 | GRIK1 (0.50) | GSRGRIK1GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL14742380 | 0.78 | GRIK1 (0.50) | GSRGRIK1GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL6941414 | 0.78 | GRIK1 (0.50) | GSRGRIK1GRIK2GRM1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115286738-A | Polyacrylic acid aspartate resin and preparation method thereof | 佛山市万化科技有限公司 | 2022-11-04 | — | — | CN | disclosed |