SCHEMBL28903754

SCHEMBL28903754

CC(C)=C(O[SiH3])c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.39
CES1 P23141 4/20 0.39
TSHR P16473 4/20 0.38
LMNA P02545 3/20 0.38
MAPK1 P28482 2/20 0.38
HTT P42858 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ELANE P08246 1/20 0.36
F2 P00734 1/20 0.36
ALDH1A1 P00352 5/20 0.35
NAPRT Q6XQN6 2/20 0.35
DAO P14920 1/20 0.35
ESR1 P03372 2/20 0.34
MAPT P10636 2/20 0.33
CYP3A4 P08684 1/20 0.33
HSD17B10 Q99714 3/20 0.32
TDP1 Q9NUW8 2/20 0.32
SLC6A3 Q01959 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9311224 0.80 TSHR (0.52) CES2CES1TSHRLMNAMAPK1
SCHEMBL9719608 0.80 CES2 (0.42) CES2CES1TSHRLMNAMAPK1
SCHEMBL9310344 0.74 ELANE (0.48) CES2CES1MAPK1L3MBTL1ELANE
SCHEMBL11807023 0.73 TSHR (0.47) TSHRLMNAMAPK1HTTL3MBTL1
SCHEMBL28884009 0.71 ESR1 (0.43) CES2CES1TSHRLMNAMAPK1
SCHEMBL16486462 0.70 CES2 (0.42) CES2CES1TSHRLMNAMAPK1
SCHEMBL10478974 0.70 CES2 (0.43) CES2CES1TSHRLMNAMAPK1
SCHEMBL10873087 0.69 TSHR (0.56) CES2CES1TSHRLMNAMAPK1
SCHEMBL1603720 0.69 TSHR (0.56) CES2CES1TSHRLMNAMAPK1
SCHEMBL4019330 0.69 TSHR (0.56) CES2CES1TSHRLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112010881-B Alkenyl boron compound and preparation method and application thereof 中国科学院兰州化学物理研究所 2021-09-03 CN disclosed
CN-112010881-A Alkenyl boron compound and preparation method and application thereof 中国科学院兰州化学物理研究所 2020-12-01 CN disclosed