Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5071855 | 0.77 | CYP1A2 (0.50) | HTTKMT2AKDR | |
| SCHEMBL1451430 | 0.77 | MAP4K4 (0.34) | DYRK1AKMT2A | |
| SCHEMBL28330304 | 0.73 | ALDH1A1 (0.36) | HTTKMT2A | |
| SCHEMBL944985 | 0.71 | HTT (0.41) | HTT | |
| SCHEMBL4402445 | 0.69 | CYP2A6 (0.34) | BIRC5HTTKMT2A | |
| SCHEMBL80566 | 0.68 | EGFR (0.47) | — | |
| SCHEMBL271715 | 0.67 | BIRC5 (0.59) | BIRC5KMT2AALPLKDR | |
| SCHEMBL18594 | 0.67 | ALDH1A1 (0.44) | HTTKMT2A | |
| SCHEMBL25148 | 0.67 | GPR3 (0.50) | — | |
| SCHEMBL294396 | 0.66 | RARB (0.41) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112020500-A | Aminopyridine derivatives as inhibitors of phosphatidylinositol phosphokinase | 拉文纳制药公司 | 2020-12-01 | — | — | CN | disclosed |