SCHEMBL25148

SCHEMBL25148

[c]1cccc2c1cnc1ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 3/20 0.50
KDM4E B2RXH2 2/20 0.50
ERN1 O75460 1/20 0.37
MAPT P10636 1/20 0.37
TOP2A P11388 2/20 0.37
PDPK1 O15530 2/20 0.36
NCF1 P14598 1/20 0.35
PI4KA P42356 1/20 0.35
PI4K2B Q8TCG2 1/20 0.35
PI4K2A Q9BTU6 1/20 0.35
PI4KB Q9UBF8 1/20 0.35
PDE4A P27815 1/20 0.35
PDE4B Q07343 1/20 0.35
PDE4C Q08493 1/20 0.35
PDE4D Q08499 1/20 0.35
CYP3A4 P08684 1/20 0.34
LOXL2 Q9Y4K0 1/20 0.33
ADORA2A P29274 1/20 0.33
CA12 O43570 1/20 0.33
PARP1 P09874 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14694125 0.76 KDM4E (0.41) GPR3KDM4EERN1MAPTNCF1
SCHEMBL9480468 0.74 MAPT (0.61) KDM4EERN1MAPTNCF1CYP3A4
SCHEMBL26597 0.73 KDM4E (0.57) GPR3KDM4EERN1MAPTTOP2A
SCHEMBL19020845 0.73 GPR3 (0.68) GPR3KDM4EERN1MAPTTOP2A
SCHEMBL28260376 0.71 KDM4E (0.45) GPR3KDM4EMAPTTOP2APDPK1
SCHEMBL1260006 0.71 LMNA (0.36) GPR3KDM4EMAPTSMN1; SMN2
SCHEMBL12471686 0.71 DCPS (0.38) GPR3KDM4EMAPTPDPK1ADORA2A
SCHEMBL2411016 0.70 CYP1A2 (0.32)
SCHEMBL2408455 0.70 CYP1A2 (0.31)
SCHEMBL4408 0.69 KDM4E (0.57) GPR3KDM4EMAPTTOP2APDPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2024 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE49118-E1 Material for organic electroluminescence device and electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2022-06-28 US claimed
CN-112390811-B Dithia-anthrone derivative and preparation method and application thereof 中国科学院理化技术研究所 2022-03-04 CN claimed
CN-114057711-A Anthracene ketone spiro derivative and preparation method and application thereof 中国科学院理化技术研究所 2022-02-18 CN claimed
CN-107556298-B Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element 出光兴产株式会社 2021-12-21 CN claimed
CN-107586290-B Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element 出光兴产株式会社 2021-05-11 CN claimed
CN-112390811-A Dithia-anthrone derivative and preparation method and application thereof 中国科学院理化技术研究所 2021-02-23 CN claimed
CN-110551054-A maleimide derivative, and preparation method and application thereof TECHNICAL INST PHYSICS & CHEMISTRY CAS 2019-12-10 CN claimed
US-10283717-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2019-05-07 US claimed
EP-2213641-B1 FUSED AROMATIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO (JP) 2018-05-16 EP claimed
US-20180090685-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2018-03-29 US claimed
CN-101414662-B organic electron transport and/or hole blocking material, and synthesis method and application thereof CHINESE ACAD TECH INST PHYSICS 2011-01-12 CN claimed
CN-101935299-A Organic electron transport and/or hole blocking material, and synthesis method and application thereof CHINESE ACAD TECH INST PHYSICS 2011-01-05 CN claimed
CN-101735800-A organic electron transport and/or hole blocking material and synthetic method and application thereof CHINESE ACAD TECH INST PHYSICS 2010-06-16 CN claimed
CN-101712867-A Organic electron transport and/or hole blocking material, and synthesis method and application thereof CHINESE ACAD TECH INST PHYSICS 2010-05-26 CN claimed
US-20090102356-A1 NOVEL ORGANIC COMPOUND HAVING ELECTRON-TRANSPORTING AND/OR HOLE-BLOCKING PERFORMANCE AND ITS USE AND OLEDs COMPRISING THE COMPOUND TECHNICAL INSTITUTE OF PHYSICS AND CHEMISTRY OF CHINESE ACADEMY OF SCIENCES (CN) 2009-04-23 US claimed
CN-101414661-A Organic electron transport and/or hole blocking material, and synthesis method and application thereof CHINESE ACAD TECH INST PHYSICS (CN) 2009-04-22 CN claimed
CN-101412907-A Organic electroluminescent material and its synthesis method and use CHINESE ACAD TECH INST PHYSICS (CN) 2009-04-22 CN claimed
CN-101414662-A Organic electron transport and/or hole blocking material, and synthesis method and application thereof CHINESE ACAD TECH INST PHYSICS (CN) 2009-04-22 CN claimed
US-20090043116-A1 HETERO-POLYCYCLIC COMPOUNDS, AND COLORING MATTERS, PIGMENTS, DYES, COLOR-CHANGING MATERIAL COMPOSITIONS, AND COLOR-CHANGING FILMS, MADE BY USING THE COMPOUNDS IDEMITSU KOSAN CO., LTD. (JP) 2009-02-12 US claimed
CN-101177608-A Material for organic electroluminescent device and organic electroluminescent device using the same IDEMITSU KOSAN CO (JP) 2008-05-14 CN claimed