Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.48 |
| ▸ | TUBB | P07437 | 2/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28496249 | 0.84 | ESR1 (0.55) | KDM4EKMT2AMAPTPTGS2ALDH1A1 | |
| SCHEMBL28490064 | 0.79 | KIF11 (0.46) | PTGS2TNKSPARP1TNKS2CNR1 | |
| SCHEMBL28486475 | 0.78 | HTR2B (0.45) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7039067 | 0.77 | PTGS2 (0.72) | KDM4EKMT2AMAPTPTGS2PTGS1 | |
| SCHEMBL7042910 | 0.77 | PTGS2 (0.72) | KDM4EKMT2AMAPTPTGS2PTGS1 | |
| SCHEMBL8995241 | 0.77 | ALOX5 (0.57) | KDM4EKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL31053083 | 0.76 | KDM4E (0.57) | KDM4EKMT2AMAPTPTGS2PTGS1 | |
| SCHEMBL1637807 | 0.76 | KDM4E (0.57) | KDM4EKMT2AMAPTPTGS2PTGS1 | |
| Indoxole SCHEMBL29519430 | 0.76 | PTGS2 (0.76) | KDM4EKMT2AMAPTPTGS2PTGS1 | |
| Indoxole SCHEMBL42592 | 0.76 | PTGS2 (0.76) | KDM4EKMT2AMAPTPTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848488-B | Method for synthesizing 3-selenoindole derivative | 温州医科大学 | 2022-12-27 | — | — | CN | disclosed |
| CN-111848488-A | Method for synthesizing 3-selenoindole derivative | 温州医科大学 | 2020-10-30 | — | — | CN | disclosed |