SCHEMBL28905907

SCHEMBL28905907

CC(O)(C(=O)O)c1ccc(-c2cccs2)cc1

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HDAC2 Q92769 9/20 0.47
HDAC1 Q13547 8/20 0.47
HDAC3 O15379 6/20 0.47
FFAR1 O14842 1/20 0.44
LTA4H P09960 1/20 0.42
ERN1 O75460 1/20 0.42
KCNH2 Q12809 1/20 0.41
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
EGLN1 Q9GZT9 1/20 0.41
ABL1 P00519 1/20 0.40
BCR P11274 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7571943 0.77 CYP2C9 (0.64)
SCHEMBL1623633 0.77 LTA4H (0.52) HDAC2HDAC1HDAC3LTA4HERN1
SCHEMBL7990521 0.77 CYP2C9 (0.64)
SCHEMBL5047387 0.77 CYP2C9 (0.64)
Methane SCHEMBL27303630 0.75 LTA4H (0.50) HDAC2HDAC1HDAC3LTA4HERN1
Acetic Acid SCHEMBL27477993 0.75 KDM4E (0.52) HDAC2HDAC1HDAC3FFAR1LTA4H
SCHEMBL16546585 0.74 LTA4H (0.48) HDAC2HDAC1HDAC3LTA4HERN1
SCHEMBL11844486 0.74 KIF11 (0.52) FFAR1PPARGPPARA
SCHEMBL10715065 0.74 RAB9A (0.55) HDAC1
SCHEMBL14082862 0.74 HDAC1 (0.50) HDAC2HDAC1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115108901-A Synthetic method of alpha-hydroxycarboxylic acid compound 四川大学 2022-09-27 CN disclosed