Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 6/20 | 0.56 |
| ▸ | MAP3K11 | Q16584 | 3/20 | 0.53 |
| ▸ | TNIK | Q9UKE5 | 6/20 | 0.51 |
| ▸ | IL2 | P60568 | 3/20 | 0.49 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | SGK1 | O00141 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21592809 | 0.91 | MAP4K1 (0.57) | MAP4K1MAP3K11TNIKIL2 | |
| SCHEMBL28517248 | 0.86 | MAP4K1 (0.64) | MAP4K1MAP3K11TNIKIL2CAMKK2 | |
| SCHEMBL21592695 | 0.86 | MAP4K1 (0.56) | MAP4K1MAP3K11TNIKIL2 | |
| SCHEMBL21592832 | 0.85 | MAP3K11 (0.54) | MAP4K1MAP3K11TNIKIL2 | |
| SCHEMBL28499799 | 0.85 | SGK1 (0.63) | MAP4K1MAP3K11TNIKIL2CAMKK2 | |
| SCHEMBL28507129 | 0.84 | TNIK (0.59) | MAP4K1MAP3K11TNIKIL2SGK1 | |
| SCHEMBL21592846 | 0.84 | MAP3K11 (0.53) | MAP4K1MAP3K11TNIKIL2 | |
| SCHEMBL21592774 | 0.83 | MAP4K1 (0.71) | MAP4K1MAP3K11TNIKIL2CAMKK2 | |
| SCHEMBL21592939 | 0.83 | MAP4K1 (0.56) | MAP4K1MAP3K11TNIKIL2CAMKK2 | |
| SCHEMBL28513938 | 0.82 | MAP4K1 (0.56) | MAP4K1MAP3K11TNIKIL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112243439-A | Pyrrolo [2,3-B ] pyridines or pyrrolo [2,3-B ] pyrazines as HPK1 inhibitors and uses thereof | 百济神州有限公司 | 2021-01-19 | — | — | CN | disclosed |