SCHEMBL28906260

SCHEMBL28906260

CCCCCCCCN(c1ccccc1)C(C)C#N

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.42
JAK2 O60674 1/20 0.42
RAB9A P51151 1/20 0.42
PAX8 Q06710 1/20 0.42
KCNH2 Q12809 7/20 0.40
TACR1 P25103 1/20 0.39
SIGMAR1 Q99720 2/20 0.35
MMP1 P03956 1/20 0.35
MMP3 P08254 1/20 0.35
EBP Q15125 1/20 0.35
ICMT O60725 1/20 0.35
ALB P02768 1/20 0.35
ALDH1A1 P00352 1/20 0.34
DRD2 P14416 1/20 0.34
OPRM1 P35372 1/20 0.34
DRD3 P35462 1/20 0.34
OPRD1 P41143 1/20 0.34
OPRK1 P41145 1/20 0.34
TAAR1 Q96RJ0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10491083 1.00 NPC1 (0.42) NPC1JAK2RAB9APAX8KCNH2
SCHEMBL9651810 0.94 TDP1 (0.37) NPC1JAK2RAB9APAX8KCNH2
SCHEMBL11702180 0.87 KCNN4 (0.38) ALDH1A1DRD3TAAR1
SCHEMBL6675337 0.80 MAPT (0.41) ALDH1A1TAAR1
SCHEMBL8438009 0.79 NPC1 (0.45) NPC1JAK2RAB9APAX8KCNH2
SCHEMBL28644337 0.79 TDP1 (0.38) NPC1JAK2RAB9APAX8KCNH2
SCHEMBL11706536 0.78 TP53 (0.41) NPC1RAB9APAX8ALDH1A1
SCHEMBL8436030 0.78 NPC1 (0.44) NPC1JAK2RAB9APAX8KCNH2
SCHEMBL8767767 0.78 TAAR1 (0.44) KCNH2SIGMAR1EBPOPRM1DRD3
SCHEMBL7774483 0.76 NPC1 (0.43) NPC1JAK2RAB9APAX8KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115279839-A Dye composition 纪和化学工业株式会社 2022-11-01 CN disclosed
CN-115244139-A Dye for dyeing with supercritical carbon dioxide 国立大学法人福井大学 2022-10-25 CN disclosed