Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.42 |
| ▸ | TACR1 | P25103 | 3/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | ICMT | O60725 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1812827 | 0.89 | ESRRG (0.34) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL8436030 | 0.88 | NPC1 (0.44) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL95222 | 0.87 | SIGMAR1 (0.36) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL7774483 | 0.87 | NPC1 (0.43) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL25684761 | 0.85 | TAAR1 (0.39) | SIGMAR1 | |
| SCHEMBL3956329 | 0.85 | TAAR1 (0.39) | SIGMAR1 | |
| SCHEMBL27329621 | 0.85 | ADRA2C (0.37) | SIGMAR1 | |
| SCHEMBL17045962 | 0.84 | TAAR1 (0.38) | SIGMAR1 | |
| SCHEMBL7163078 | 0.83 | NPC1 (0.39) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL8438389 | 0.79 | NPC1 (0.39) | NPC1JAK2RAB9APAX8KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5865857-A | COLORFASTNESS; PHOTOSTABILITY | ZENECA LIMITED (GB) | 1999-02-02 | — | — | US | disclosed |
| EP-0667887-B1 | DYES | ZENECA LTD (GB) | 1998-09-23 | — | — | EP | disclosed |
| US-5660598-A | PRODUCE LIGHTFAST BLUE TO GREEN SHADES ON SYNTHETIC TEXTILES | ZENECA LIMITED (GB) | 1997-08-26 | — | — | US | disclosed |
| EP-0667887-A1 | DYES | ZENECA LIMITED (GB) | 1995-08-23 | — | — | EP | disclosed |
| WO-1994010248-A1 | DYES | ZENECA LIMITED (GB) | 1994-05-11 | — | — | WO | disclosed |