Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.44 |
| ▸ | EBP | Q15125 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11693861 | 0.86 | ALDH1A1 (0.37) | TAAR1SIGMAR1AOC3EBPCHRM2 | |
| SCHEMBL11702180 | 0.83 | KCNN4 (0.38) | TAAR1HTR1ADRD3MAOB | |
| SCHEMBL10932143 | 0.83 | ALDH1A1 (0.46) | TAAR1SIGMAR1AOC3SLC6A2SLC6A4 | |
| SCHEMBL11813263 | 0.80 | TAAR1 (0.52) | TAAR1SIGMAR1AOC3CHRM2HTR1A | |
| SCHEMBL9651810 | 0.80 | TDP1 (0.37) | TAAR1OPRM1KCNH2 | |
| SCHEMBL6675337 | 0.79 | MAPT (0.41) | TAAR1MAOB | |
| SCHEMBL10491083 | 0.78 | NPC1 (0.42) | TAAR1SIGMAR1EBPOPRM1DRD3 | |
| SCHEMBL28906260 | 0.78 | NPC1 (0.42) | TAAR1SIGMAR1EBPOPRM1DRD3 | |
| SCHEMBL11674257 | 0.75 | NR1H2 (0.33) | TAAR1SIGMAR1EBPOPRM1DRD3 | |
| SCHEMBL11215102 | 0.73 | RAD52 (0.40) | CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519459-B1 | Disperse dye mixture | DYSTAR JAPAN LTD (JP) | 1997-09-03 | — | — | EP | disclosed |
| US-5304222-A | Monoazo benzothiazole disperse dye mixture | HOECHST MITSUBISHI KASEI CO., LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0240902-B1 | PROCESS FOR THE MANUFACTURE OF AZO DYES | CASSELLA Aktiengesellschaft (DE) | 1993-06-09 | — | — | EP | disclosed |
| EP-0519459-A2 | Disperse dye mixture | DyStar Japan Ltd. (JP) | 1992-12-23 | — | — | EP | disclosed |
| US-4795807-A | Preparation of azo dyestuffs by diazotization and coupling in the presence of an ester | CASSELLA AKTIENGESELLSCHAFT (DE) | 1989-01-03 | — | — | US | disclosed |
| EP-0240902-A2 | Process for the manufacture of azo dyes | CASSELLA Aktiengesellschaft (DE) | 1987-10-14 | — | — | EP | disclosed |
| EP-0098445-A2 | Process for preparing 2-amino-5-nitro-thiazole | CASSELLA Aktiengesellschaft (DE) | 1984-01-18 | — | — | EP | disclosed |
| US-4313872-A | MONDAZO AND DISAZO DYES | CASSELLA AKTIENGESELLSCHAFT (DE) | 1982-02-02 | — | — | US | disclosed |
| US-3939142-A | Phenylazophenyl dyestuff | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-02-17 | — | — | US | disclosed |