SCHEMBL6675337

SCHEMBL6675337

CCN(c1ccccc1)C(C)C#N

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.41
TP53 P04637 1/20 0.41
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TSHR P16473 2/20 0.37
ALDH1A1 P00352 1/20 0.37
GLA P06280 1/20 0.37
NR1H2 P55055 7/20 0.36
NR1H3 Q13133 7/20 0.36
MAOB P27338 1/20 0.35
TAAR1 Q96RJ0 2/20 0.35
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
S1PR1 P21453 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11702180 0.85 KCNN4 (0.38) MAPTTP53CRHBPCRHR2NPSR1
SCHEMBL11633652 0.83 S1PR1 (0.30) S1PR1
SCHEMBL28458344 0.82 MAPT (0.42) MAPTTP53CRHBPCRHR2NPSR1
SCHEMBL9651810 0.82 TDP1 (0.37) MAPTTP53CRHBPCRHR2NPSR1
SCHEMBL10932143 0.81 ALDH1A1 (0.46) CRHBPCRHR2TSHRALDH1A1MAOB
SCHEMBL8394632 0.81 TP53 (0.45) MAPTTP53TSHRALDH1A1S1PR1
SCHEMBL28906260 0.80 NPC1 (0.42) ALDH1A1TAAR1
SCHEMBL10491083 0.80 NPC1 (0.42) ALDH1A1TAAR1
SCHEMBL11704959 0.79 MAPT (0.40) MAPTTP53CRHBPCRHR2NPSR1
SCHEMBL8767767 0.79 TAAR1 (0.44) MAOBTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-221207147-U Impurity filtering equipment for N-ethyl-N-cyanoethylaniline 嘉兴富成化工科技股份有限公司 2024-06-25 CN claimed
CN-116814089-B Process for synthesizing disperse dye and disperse dye 山东安诺其精细化工有限公司 2024-06-21 CN claimed
CN-220696722-U Mixed reaction kettle for producing N-ethyl-N-cyanoethylaniline 宿州恒昶生物科技有限公司 2024-04-02 CN claimed
CN-219964414-U Tail gas recovery device for producing N-ethyl-N-cyanoethylaniline 宿州恒昶生物科技有限公司 2023-11-07 CN claimed
CN-116814089-A Process for synthesizing disperse dye and disperse dye 山东安诺其精细化工有限公司 2023-09-29 CN claimed
CN-112500713-B Continuous preparation method of azo disperse dye 浙江龙盛染料化工有限公司 2023-04-14 CN claimed
CN-217614773-U Low energy consumption reation kettle is used in N-ethyl-N-cyanoethylaniline production 嘉兴富成化工科技股份有限公司 2022-10-21 CN claimed
CN-115044226-A 3-amino-5-nitrobenzoisothiazole-based dye and preparation method thereof 金塔县晋泰森新材料科技有限公司 2022-09-13 CN claimed
CN-113968796-A Preparation method of azo dye with excellent environment-friendly application performance 安徽清科瑞洁新材料有限公司 2022-01-25 CN claimed
CN-215137023-U Tail gas recovery device is used in production of N-ethyl-N-cyanoethylaniline 嘉兴富成化工科技股份有限公司 2021-12-14 CN claimed
CN-112500713-A Continuous preparation method of azo disperse dye 浙江龙盛染料化工有限公司 2021-03-16 CN claimed
CN-212263223-U Waste gas collecting device in production N-ethyl-N-cyanoethylaniline process 吴江梅堰三友染料化工有限公司 2021-01-01 CN claimed
JP-9003352-A None JP disclosed
JP-56047450-A None JP disclosed
JP-59161462-A None JP disclosed
JP-57177059-A None JP disclosed
US-4036825-A DYES FOR CELLULOSE OR NITROGEN-CONTAINING FIBERS HOECHST AKTIENGESELLSCHAFT (DT) 1977-07-19 US disclosed
US-4002631-A HEAT-SENSITIVE COLOR FORMERS HODOGAYA CHEMICAL CO., LTD. (JA) 1977-01-11 US disclosed
US-3963747-A Basic arylmercaptonaphtholactam dyes BASF AKTIENGESELLSCHAFT (DT) 1976-06-15 US disclosed
US-3945991-A Heterocyclic azo compounds containing a quaternated hydrazide group CIBA-GEIGY AG (CH) 1976-03-23 US disclosed