SCHEMBL28906287

SCHEMBL28906287

C[Si](C)(C)CCc1ccc(O[PH]=O)cc1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
PPARA Q07869 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
F2RL1 P55085 1/20 0.33
ALDH1A1 P00352 3/20 0.33
POLB P06746 2/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15952484 0.78 ESR1 (0.40) TAAR1
SCHEMBL28344922 0.76 TAAR1 (0.36) SMN1; SMN2TAAR1PPARAF2RL1ALDH1A1
SCHEMBL28906297 0.76 DAO (0.34) SMN1; SMN2TAAR1PPARAF2RL1ALDH1A1
SCHEMBL24602755 0.70 CYP1A2 (0.52) SMN1; SMN2TAAR1MEN1KMT2AALDH1A1
SCHEMBL17722492 0.70 LPL (0.46) ALDH1A1RAB9A
SCHEMBL20536283 0.69 PPARA (0.35) TAAR1PPARAALDH1A1POLB
SCHEMBL21925685 0.69 CA2 (0.41) PPARA
SCHEMBL13923732 0.69 ESR1 (0.60) TAAR1KMT2AALDH1A1
SCHEMBL20004512 0.69 TAAR1 (0.50) SMN1; SMN2TAAR1POLBRAB9A
SCHEMBL3211356 0.69 GFER (0.59) SMN1; SMN2TAAR1ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115417896-A P-C bond-containing phosphorus-nitrogen triazine flame retardant and preparation method thereof 西北大学 2022-12-02 CN disclosed