Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.64 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.61 |
| ▸ | GUSB | P08236 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28906328 | 0.84 | AR (0.63) | ARCHRNA7MAPTL3MBTL1MAOB | |
| SCHEMBL28906376 | 0.81 | CHRNA7 (0.73) | CHRNA7MAPTNPC1L3MBTL1KDM4E | |
| SCHEMBL7196342 | 0.78 | CHRNA7 (0.79) | CHRNA7GUSB | |
| SCHEMBL7196345 | 0.78 | CHRNA7 (0.79) | CHRNA7GUSB | |
| SCHEMBL13857110 | 0.77 | AR (1.00) | ARCHRNA7GUSBMAPTMAOB | |
| SCHEMBL19236264 | 0.76 | CHRNA7 (1.00) | CHRNA7GUSB | |
| SCHEMBL30383155 | 0.76 | TYR (0.82) | CHRNA7MAPTMAOBPKMKMT2A | |
| SCHEMBL5085108 | 0.75 | AR (0.88) | ARGUSBMAPTNPC1L3MBTL1 | |
| SCHEMBL5085100 | 0.75 | AR (0.88) | ARGUSBMAPTNPC1L3MBTL1 | |
| SCHEMBL7193420 | 0.75 | MAOA (0.72) | ARMAPTNPC1L3MBTL1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304513-A | Chalcone derivative with anti-inflammatory activity and synthesis method and application thereof | 湖北科技学院 | 2022-11-08 | — | — | CN | disclosed |