Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 4/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28513286 | 0.84 | ITGB1 (0.46) | TLR8LTA4HPLA2G2ADHFR | |
| SCHEMBL28521021 | 0.84 | ITGB1 (0.46) | TLR8LTA4HPLA2G2ADHFR | |
| SCHEMBL28905528 | 0.82 | DHFR (0.56) | TLR8DHFR | |
| SCHEMBL28905581 | 0.82 | DHFR (0.56) | TLR8DHFR | |
| SCHEMBL28960353 | 0.81 | TLR8 (0.51) | TLR8NCF1 | |
| SCHEMBL28514135 | 0.77 | NCF1 (0.45) | NCF1 | |
| SCHEMBL15922866 | 0.73 | S1PR2 (0.48) | TLR8S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL28521004 | 0.73 | TLR8 (0.53) | TLR8NCF1 | |
| SCHEMBL28514975 | 0.73 | TLR8 (0.53) | TLR8NCF1 | |
| SCHEMBL28516032 | 0.72 | TLR8 (0.56) | TLR8NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250142-B | Amine compounds having anti-inflammatory, antifungal, antiparasitic and anticancer activity | 维尔斯达医疗公司 | 2021-01-26 | — | — | CN | disclosed |