Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.35 |
| ▸ | RHEB | Q15382 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 8/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28510258 | 0.86 | TYRO3 (0.36) | LOXL2RHEBSYKROCK1MAP4K1 | |
| SCHEMBL18049133 | 0.85 | LOXL2 (0.44) | LOXL2ROCK1 | |
| Hydrochloric Acid SCHEMBL18049171 | 0.84 | LOXL2 (0.44) | LOXL2ROCK1 | |
| SCHEMBL18361990 | 0.81 | LOXL2 (0.57) | LOXL2RHEBSYKROCK1MAP4K1 | |
| SCHEMBL18361992 | 0.79 | LOXL2 (0.38) | LOXL2RHEBSYKMAP4K1TYRO3 | |
| SCHEMBL19755754 | 0.74 | LOXL2 (0.41) | LOXL2SYKROCK1MAP4K1HTR3A | |
| SCHEMBL19755757 | 0.74 | LOXL2 (0.40) | LOXL2SYKMAP4K1HTR3A | |
| SCHEMBL20337899 | 0.73 | ROCK1 (0.55) | RHEBROCK1 | |
| SCHEMBL18361988 | 0.73 | FFAR4 (0.39) | SYKROCK1MAP4K1HTR3AFFAR4 | |
| SCHEMBL19739420 | 0.72 | LOXL2 (0.37) | LOXL2RHEBSYKMAP4K1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107624110-B | Lysyl oxidase-like 2 inhibitors and uses thereof | 法玛克亚公司 | 2021-01-26 | — | — | CN | disclosed |