Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 4/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.32 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18072475 | 0.87 | LOXL2 (0.55) | LOXL2SCN9ASYKIRAK4MAP4K1 | |
| SCHEMBL19755754 | 0.83 | LOXL2 (0.41) | LOXL2SYKHTR3AIRAK4MAP4K1 | |
| SCHEMBL18361992 | 0.80 | LOXL2 (0.38) | LOXL2SCN9ASYKHTR3AIRAK4 | |
| SCHEMBL28906716 | 0.74 | LOXL2 (0.35) | LOXL2SYKHTR3AMAP4K1 | |
| SCHEMBL19739420 | 0.73 | LOXL2 (0.37) | LOXL2SYKHTR3AIRAK4MAP4K1 | |
| SCHEMBL28567884 | 0.73 | LOXL2 (0.39) | LOXL2SYKHTR3AIRAK4MAP4K1 | |
| SCHEMBL28510258 | 0.73 | TYRO3 (0.36) | LOXL2SYKHTR3AIRAK4MAP4K1 | |
| Hydrochloric Acid SCHEMBL28574601 | 0.72 | LOXL2 (0.39) | LOXL2SYKHTR3AMAP4K1NPSR1 | |
| SCHEMBL18049928 | 0.72 | LOXL2 (0.55) | LOXL2 | |
| SCHEMBL18361990 | 0.72 | LOXL2 (0.57) | LOXL2SYKHTR3AIRAK4MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170369443-A1 | FLUORINATED LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. | 2017-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170369443-A1 | FLUORINATED LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | LOXL2, LOXL1, LOX | LOXL2 1/4885GRM5 4081/4885SCN9A 4216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.