Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21176556 | 0.81 | CFTR (0.57) | CFTRKDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL7550401 | 0.78 | CFTR (0.57) | CFTRKDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL7554661 | 0.77 | KMT2A (0.59) | CFTRKDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL29243244 | 0.75 | CFTR (0.50) | CFTRKDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL22263091 | 0.75 | CFTR (0.73) | CFTRKDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL167426 | 0.74 | CFTR (0.71) | CFTRKDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL28510653 | 0.72 | CFTR (0.47) | CFTRKDM4EMAPTMRGPRX4 | |
| SCHEMBL694388 | 0.72 | CFTR (0.69) | CFTRKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL422201 | 0.72 | CFTR (0.69) | CFTRKDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL28172968 | 0.72 | CFTR (0.69) | CFTRKDM4EMAPTHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112204008-B | Sulfonylaminobenzamides and sulfonylaminobenzamide derivatives | 奥索生物公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-112204008-A | Sulphonylaminobenzylamide and sulphonylaminobenzamide derivatives | 吉利德科学公司 | 2021-01-08 | — | — | CN | disclosed |