Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28510653 | 0.85 | CFTR (0.47) | CFTRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28906829 | 0.84 | SLC6A4 (0.36) | CFTRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL21176556 | 0.77 | CFTR (0.57) | CFTRKDM4EMAPTMRGPRX4ALDH1A1 | |
| SCHEMBL28616717 | 0.77 | PTPN1 (0.33) | CFTRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28906830 | 0.75 | CFTR (0.55) | CFTRKDM4EMAPTMRGPRX4ALDH1A1 | |
| SCHEMBL4949996 | 0.75 | CFTR (0.57) | CFTRTRPV1KDM4ESOS1ALDH1A1 | |
| SCHEMBL425243 | 0.73 | CFTR (0.67) | CFTRKDM4EMAPTSOS1MRGPRX4 | |
| SCHEMBL7550401 | 0.72 | CFTR (0.57) | CFTRKDM4EMAPTMRGPRX4ALDH1A1 | |
| SCHEMBL22263091 | 0.71 | CFTR (0.73) | CFTRKDM4EMAPTMRGPRX4ALDH1A1 | |
| SCHEMBL7554661 | 0.71 | KMT2A (0.59) | CFTRKDM4EMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112204008-B | Sulfonylaminobenzamides and sulfonylaminobenzamide derivatives | 奥索生物公司 | 2024-07-05 | — | — | CN | disclosed |