Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28516915 | 0.86 | KIF11 (0.38) | PTGDR2RXFP1RORCKIF11SCN8A | |
| SCHEMBL29243244 | 0.85 | CFTR (0.50) | CFTRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29243257 | 0.83 | CFTR (0.45) | CFTRPTGDR2RXFP1RORCKIF11 | |
| SCHEMBL21176556 | 0.74 | CFTR (0.57) | CFTRKDM4EMAPTMRGPRX4 | |
| SCHEMBL11608812 | 0.73 | CFTR (0.61) | CFTRKDM4EMRGPRX4PTPN1PTPN6 | |
| SCHEMBL28906830 | 0.72 | CFTR (0.55) | CFTRKDM4EMAPTMRGPRX4 | |
| SCHEMBL23141209 | 0.71 | KDM1A (0.53) | CFTRKDM4E | |
| SCHEMBL6809217 | 0.70 | TAS2R14 (0.48) | CFTRPTGDR2RXFP1SCN8ASCN10A | |
| SCHEMBL7550401 | 0.70 | CFTR (0.57) | CFTRPOLBKDM4EMAPTMRGPRX4 | |
| SCHEMBL28906829 | 0.69 | SLC6A4 (0.36) | CFTRTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112204008-A | Sulphonylaminobenzylamide and sulphonylaminobenzamide derivatives | 吉利德科学公司 | 2021-01-08 | — | — | CN | disclosed |