Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.45 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2443486 | 0.87 | HSPB1 (0.58) | HSPB1EPAS1MAPTTDP1GAA | |
| SCHEMBL29549341 | 0.87 | HSPB1 (0.58) | HSPB1EPAS1MAPTTDP1GAA | |
| SCHEMBL28511295 | 0.83 | HSPB1 (0.56) | SMN1; SMN2HSPB1MAPTTDP1GAA | |
| SCHEMBL29845685 | 0.79 | HSPB1 (0.53) | SMN1; SMN2S1PR4HSPB1EPAS1PDE7A | |
| SCHEMBL20154998 | 0.79 | HSPB1 (0.53) | SMN1; SMN2S1PR4HSPB1EPAS1PDE7A | |
| SCHEMBL680217 | 0.79 | HSPB1 (0.47) | LMNASMN1; SMN2HSPB1MAPTTDP1 | |
| SCHEMBL30194332 | 0.79 | SLC6A2 (0.44) | POLBSMN1; SMN2EPAS1MAPTGAA | |
| SCHEMBL28509222 | 0.79 | SLC6A2 (0.44) | POLBSMN1; SMN2EPAS1MAPTGAA | |
| SCHEMBL10756271 | 0.77 | S1PR4 (0.56) | LMNAPOLBSMN1; SMN2S1PR4PDE7A | |
| SCHEMBL28520772 | 0.76 | HSPB1 (0.55) | LMNAPOLBSMN1; SMN2HSPB1PDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300154-B | Nitrogen-containing heterocyclic compound, preparation method and application thereof | 上海弘翊生物科技有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-112300154-A | Nitrogen-containing heterocyclic compound, preparation method and application thereof | 上海弘翊生物科技有限公司 | 2021-02-02 | — | — | CN | disclosed |