Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 6/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2443486 | 1.00 | HSPB1 (0.58) | HSPB1TDP1L3MBTL1GAAMAPT | |
| SCHEMBL28511295 | 0.88 | HSPB1 (0.56) | HSPB1TDP1L3MBTL1GAAMAPT | |
| SCHEMBL16049146 | 0.88 | HSPB1 (0.62) | HSPB1TDP1L3MBTL1GAAMAPT | |
| SCHEMBL16046439 | 0.88 | HSPB1 (0.66) | HSPB1TDP1L3MBTL1GAAMAPT | |
| SCHEMBL28906973 | 0.87 | LMNA (0.46) | HSPB1TDP1L3MBTL1GAAMAPT | |
| SCHEMBL28496978 | 0.86 | HSPB1 (0.60) | HSPB1TDP1L3MBTL1GAAMAPT | |
| SCHEMBL28657257 | 0.85 | HSPB1 (0.59) | HSPB1TDP1L3MBTL1GAAMAPT | |
| SCHEMBL16738733 | 0.84 | HSPB1 (0.58) | HSPB1TDP1L3MBTL1GAAMAPT | |
| SCHEMBL28520772 | 0.84 | HSPB1 (0.55) | HSPB1TDP1L3MBTL1GAAMAPT | |
| SCHEMBL16738728 | 0.84 | HSPB1 (0.54) | HSPB1TDP1L3MBTL1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300154-B | Nitrogen-containing heterocyclic compound, preparation method and application thereof | 上海弘翊生物科技有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-110041253-B | Pyridine N-oxide derivative and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-03-29 | — | — | CN | disclosed |