SCHEMBL28907669

SCHEMBL28907669

OCC1c2cc(Cl)ccc2-c2ccc(Cl)cc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.46
TRPM5 Q9NZQ8 5/20 0.38
TRPM4 Q8TD43 4/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
AHR P35869 1/20 0.38
HTR2B P41595 1/20 0.37
TP53 P04637 1/20 0.37
S100A4 P26447 1/20 0.37
SRD5A2 P31213 1/20 0.36
HRH3 Q9Y5N1 1/20 0.35
IDO1 P14902 2/20 0.34
MEN1 O00255 1/20 0.34
SLC22A1 O15245 1/20 0.34
USP2 O75604 1/20 0.34
LMNA P02545 1/20 0.34
HSP90AA1 P07900 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPT P10636 1/20 0.34
HSPD1 P10809 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28540993 0.91 HRH3 (0.46) CYP1A2TRPM5TRPM4S100A4HRH3
SCHEMBL9542340 0.83 CYP1A2 (0.44) CYP1A2TRPM5TRPM4AHRHTR2B
SCHEMBL28545962 0.79 KCNH2 (0.43) HSD17B10TP53LMNACYP3A4HSPD1
SCHEMBL8993321 0.78 HTR2B (0.40) CYP1A2AHRHTR2BS100A4LMNA
SCHEMBL30633075 0.78 HTR2B (0.40) CYP1A2AHRHTR2BS100A4LMNA
SCHEMBL9631975 0.78 AHR (0.48) CYP1A2TRPM5TRPM4TSHRHSD17B10
SCHEMBL8993310 0.75 IDO1 (0.36) CYP1A2AHRHTR2BTP53S100A4
SCHEMBL25282118 0.74 HRH3 (0.35) HRH3
SCHEMBL1569369 0.74 S100A4 (0.37) S100A4HRH3ALOX15
SCHEMBL29844508 0.74 CDK5 (0.37) TSHRHSD17B10TP53S100A4HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112209651-B Concrete accelerator and preparation method thereof 海南佳益混凝土有限公司 2021-07-30 CN disclosed
CN-112209651-A Concrete accelerator and preparation method thereof 南京创企和利科技有限公司 2021-01-12 CN disclosed