Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | TRPM4 | Q8TD43 | 3/20 | 0.33 |
| ▸ | TRPM5 | Q9NZQ8 | 3/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.32 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28907669 | 0.83 | CYP1A2 (0.46) | CYP1A2HTR2BS100A4TRPM4TRPM5 | |
| SCHEMBL9544149 | 0.76 | TDO2 (0.36) | CYP1A2TDO2TRPM5MEN1MAPT | |
| SCHEMBL28540993 | 0.76 | HRH3 (0.46) | CYP1A2TDO2S100A4TRPM4TRPM5 | |
| SCHEMBL8993321 | 0.75 | HTR2B (0.40) | CYP1A2HTR2BS100A4LMNAHPGD | |
| SCHEMBL30633075 | 0.75 | HTR2B (0.40) | CYP1A2HTR2BS100A4LMNAHPGD | |
| SCHEMBL22049533 | 0.71 | TERT (0.37) | TRPM4TRPM5 | |
| SCHEMBL2231461 | 0.70 | TDO2 (0.61) | CYP1A2TDO2HTR2BLMNACYP3A4 | |
| SCHEMBL30413587 | 0.70 | TDO2 (0.61) | CYP1A2TDO2HTR2BLMNACYP3A4 | |
| SCHEMBL29145549 | 0.69 | CYP11B1 (0.44) | CYP1A2MEN1CYP3A4MAPTHPGD | |
| SCHEMBL30633024 | 0.69 | CYP11B1 (0.44) | CYP1A2MEN1CYP3A4MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993011764-A1 | FLUORENYL DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | SCIOS NOVA INC. (US) | 1993-06-24 | — | — | WO | disclosed |