Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | S100A4 | P26447 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | PPOX | P50336 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542340 | 0.80 | CYP1A2 (0.44) | IDO1S100A4CYP1A2HTR2BCHRNB2 | |
| SCHEMBL8993321 | 0.75 | HTR2B (0.40) | S100A4CYP1A2HTR2BCHRNB2CHRNA4 | |
| SCHEMBL28907669 | 0.75 | CYP1A2 (0.46) | IDO1S100A4CYP1A2HTR2BAHR | |
| SCHEMBL30633075 | 0.75 | HTR2B (0.40) | S100A4CYP1A2HTR2BCHRNB2CHRNA4 | |
| SCHEMBL3073671 | 0.70 | HTR2A (0.54) | HTR2BTP53 | |
| SCHEMBL30633024 | 0.69 | CYP11B1 (0.44) | CYP1A2 | |
| SCHEMBL29145549 | 0.69 | CYP11B1 (0.44) | CYP1A2 | |
| SCHEMBL28540993 | 0.68 | HRH3 (0.46) | S100A4CYP1A2 | |
| SCHEMBL1452967 | 0.68 | HTR2A (0.34) | HTR2BTP53 | |
| SCHEMBL3989019 | 0.67 | S100A4 (0.41) | S100A4CYP1A2HTR2BCHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519043-A | ANTIINFLAMMATORY AGENTS WITH AMIDE, CARBAMATE OR THIOCARBAMATE GROUPS ON FLUORENE AND BENZENE | SCIOS NOVA INC. (US) | 1996-05-21 | — | — | US | disclosed |