Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL1783840 | 0.85 | DAO (0.47) | DAOTSHRNAPRTCYP1A2KMT2A | |
| Benzoic Acid SCHEMBL1785936 | 0.81 | TSHR (0.47) | DAOTSHRNAPRTCYP1A2KMT2A | |
| Benzoic Acid SCHEMBL11963082 | 0.81 | DAO (0.47) | DAOTSHRNAPRTCYP1A2KMT2A | |
| Benzoic Acid SCHEMBL2032078 | 0.79 | TSHR (0.64) | DAOTSHRNAPRTCYP1A2KMT2A | |
| Benzoic Acid SCHEMBL6934526 | 0.79 | TSHR (0.64) | DAOTSHRNAPRTCYP1A2KMT2A | |
| Benzoic Acid SCHEMBL569747 | 0.77 | TSHR (0.50) | DAOTSHRNAPRTCYP1A2KMT2A | |
| Benzoic Acid SCHEMBL1833087 | 0.77 | TSHR (0.67) | DAOTSHRNAPRTKMT2ACES2 | |
| Benzoic Acid SCHEMBL11963535 | 0.77 | DAO (0.45) | DAOTSHRNAPRTCYP1A2KMT2A | |
| Benzoic Acid SCHEMBL1071213 | 0.76 | TSHR (0.48) | DAOTSHRNAPRTCYP1A2KMT2A | |
| Benzoic Acid SCHEMBL1784830 | 0.76 | TSHR (0.48) | DAOTSHRNAPRTCYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114341254-B | Health care articles comprising random propylene-ethylene copolymers | SABIC环球技术有限责任公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-107922694-B | Process for producing low emission polypropylene | SABIC环球技术有限责任公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-114341254-A | Health care articles comprising random propylene-ethylene copolymers | SABIC环球技术有限责任公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-113056515-A | Food packaging comprising a polymer composition and use of said polymer composition for manufacturing food packaging | SABIC环球技术有限责任公司 | 2021-06-29 | — | — | CN | disclosed |
| CN-107810206-B | Procatalyst for olefin polymerization comprising aminobenzoate internal donor and 1, 3-diether internal donor in specific ratios | SABIC环球技术有限责任公司 | 2021-01-19 | — | — | CN | disclosed |
| CN-108699283-B | Composition comprising a heterophasic propylene copolymer | SABIC环球技术有限责任公司 | 2020-12-29 | — | — | CN | disclosed |