Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28908213 | 0.93 | TLR7 (0.38) | CYP3A4MAPTKCNH2 | |
| SCHEMBL28908170 | 0.92 | CYP2C19 (0.42) | HTTLMNAKMT2ACYP3A4MAPT | |
| SCHEMBL28908216 | 0.91 | RXFP1 (0.34) | HTTPOLBALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28908171 | 0.91 | POLB (0.35) | MAPTPOLBSMN1; SMN2NPC1 | |
| SCHEMBL28960551 | 0.89 | ADCY8 (0.33) | HTTPOLBALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28908212 | 0.87 | LMNA (0.32) | HTTLMNAMAPTPOLBL3MBTL1 | |
| SCHEMBL29773466 | 0.87 | LMNA (0.34) | HTTLMNAKMT2ACYP3A4MAPT | |
| SCHEMBL1795743 | 0.87 | CA1 (0.36) | HTTLMNAMAPTL3MBTL1TDP1 | |
| SCHEMBL28908196 | 0.87 | HTT (0.38) | HTTLMNAKMT2AMAPTPOLB | |
| SCHEMBL1547830 | 0.87 | MAPT (0.43) | HTTLMNAKMT2ACYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380762-A | Isoxazoline hydrazide derivative and preparation method and application thereof | 贵州大学 | 2022-04-22 | — | — | CN | disclosed |