Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23880583 | 0.84 | APP (0.44) | NPC1RAB9AAPPFFAR1NPSR1 | |
| SCHEMBL25391778 | 0.81 | NPSR1 (0.43) | NPC1RAB9AAPPFFAR1NPSR1 | |
| SCHEMBL17667983 | 0.78 | ELANE (0.42) | NPC1RAB9AAPPFFAR1NPSR1 | |
| SCHEMBL8940636 | 0.77 | NPC1 (0.57) | NPC1RAB9AAPPFFAR1GRM5 | |
| SCHEMBL9364505 | 0.76 | NPSR1 (0.46) | NPC1RAB9AAPPFFAR1NPSR1 | |
| SCHEMBL2256472 | 0.76 | LMNA (0.52) | APPFFAR1NPSR1ALDH1A1MAPT | |
| SCHEMBL1713040 | 0.76 | LMNA (0.46) | RAB9AAPPFFAR1GRM5NPSR1 | |
| SCHEMBL38695 | 0.76 | NPC1 (0.47) | NPC1RAB9AAPPFFAR1NPSR1 | |
| SCHEMBL5709263 | 0.73 | AKR1C3 (0.51) | NPC1RAB9AFFAR1NPSR1KDM4E | |
| SCHEMBL3262337 | 0.73 | LMNA (0.36) | RAB9AAPPFFAR1NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4132523-A1 | NOVEL N-ARYL OXAMIC ACIDS | Purdue Research Foundation (US) | 2023-02-15 | — | — | EP | disclosed |
| CN-115297860-A | Novel N-aryl-oxalamic acids | 普渡研究基金会 | 2022-11-04 | — | — | CN | disclosed |