Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | HNF4A | P41235 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38695 | 0.91 | NPC1 (0.47) | NPC1RAB9AKDM4EALDH1A1TSHR | |
| SCHEMBL2746516 | 0.86 | ALDH1A1 (0.52) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL28568009 | 0.81 | HPGD (0.53) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL28908443 | 0.77 | NPC1 (0.44) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL1713040 | 0.76 | LMNA (0.46) | RAB9AKDM4EALDH1A1MAPTTSHR | |
| SCHEMBL2256472 | 0.76 | LMNA (0.52) | ALDH1A1MAPTTSHRHSD17B10FFAR1 | |
| Benzene SCHEMBL27395742 | 0.74 | ALDH1A1 (0.67) | NPC1RAB9ACTNNB1BCAT2KDM4E | |
| SCHEMBL9548507 | 0.73 | ALDH1A1 (0.54) | NPC1RAB9ACTNNB1BCAT2KDM4E | |
| SCHEMBL157857 | 0.73 | NPC1 (1.00) | NPC1RAB9ACTNNB1BCAT2KDM4E | |
| Carbamic Acid SCHEMBL28336611 | 0.72 | ALDH1A1 (0.64) | NPC1RAB9ACTNNB1BCAT2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5567800-A | MOLECULAR WEIGHT CONTROLLED AROMATIC POLYIMIDES; ELONGATION, HIGH GLASS TRANSITION TEMPERATURE, TOUGHNESS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1996-10-22 | — | — | US | claimed |