Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30338328 | 0.85 | KIF11 (0.36) | ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL25816149 | 0.85 | KIF11 (0.36) | ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL28908869 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KMT2AKDM4EGAAMEN1 | |
| SCHEMBL23857271 | 0.78 | MAPT (0.56) | ALDH1A1KMT2AKDM4EGAAMEN1 | |
| SCHEMBL30882936 | 0.78 | MAPT (0.56) | ALDH1A1KMT2AKDM4EGAAMEN1 | |
| SCHEMBL30356308 | 0.78 | KIF11 (0.39) | ALDH1A1KDM4EHSD17B10MAOB | |
| SCHEMBL25815906 | 0.78 | KIF11 (0.39) | ALDH1A1KDM4EHSD17B10MAOB | |
| SCHEMBL28908701 | 0.78 | ALDH1A1 (0.48) | ALDH1A1KMT2AKDM4EGAAMEN1 | |
| SCHEMBL17386339 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KMT2AKDM4EGAAMEN1 | |
| SCHEMBL28908685 | 0.75 | TSHR (0.40) | ALDH1A1KMT2AKDM4EGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115298176-A | Compounds and their use in the treatment of bacterial infections | 豪夫迈·罗氏有限公司 | 2022-11-04 | — | — | CN | disclosed |