Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SLC2A9 | Q9NRM0 | 1/20 | 0.37 |
| ▸ | EDNRB | P24530 | 3/20 | 0.36 |
| ▸ | EDNRA | P25101 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30356308 | 1.00 | KIF11 (0.39) | KIF11SMN1; SMN2SLC22A12ALDH1A1SLC2A9 | |
| SCHEMBL25816149 | 0.81 | KIF11 (0.36) | KIF11SLC22A12ALDH1A1SLC2A9SIRT2 | |
| SCHEMBL30338328 | 0.81 | KIF11 (0.36) | KIF11SLC22A12ALDH1A1SLC2A9SIRT2 | |
| SCHEMBL7220291 | 0.80 | ACHE (0.40) | KIF11SMN1; SMN2ALDH1A1EDNRBEDNRA | |
| SCHEMBL28908862 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAOBHSD17B10 | |
| SCHEMBL13938126 | 0.76 | ACHE (0.45) | ALDH1A1EDNRBEDNRAKDM4EHSD17B10 | |
| SCHEMBL2480306 | 0.75 | ACHE (0.41) | KIF11PIM1CSNK1A1CDK5ROCK1 | |
| SCHEMBL28850201 | 0.72 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1EDNRBEDNRAKDM4E | |
| SCHEMBL916737 | 0.72 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1EDNRBEDNRAKDM4E | |
| SCHEMBL7155154 | 0.71 | CYP19A1 (0.48) | ALDH1A1KDM4ECYP19A1HSD17B10LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12448363-B2 | Kinase inhibitors | VIDYA THERAPEUTICS, INC. (US) | 2025-10-21 | — | — | US | disclosed |
| US-20230219923-A1 | KINASE INHIBITORS | VIDYA THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
| US-20230219923-A1 | KINASE INHIBITORS | VIDYA THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
| US-20230219923-A1 | KINASE INHIBITORS | VIDYA THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
| EP-4157446-A1 | KINASE INHIBITORS | GB002, Inc. (US) | 2023-04-05 | — | — | EP | disclosed |
| CN-115867346-A | Kinase inhibitors | GB005股份有限公司 | 2023-03-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12448363-B2 | Kinase inhibitors | BTK, ABL1, LYN | KIF11 3743/4885SMN1; SMN2 4070/4885SLC22A12 4839/4885 |
| US-20230219923-A1 | KINASE INHIBITORS | BTK, ABL1, LYN | KIF11 3743/4885SMN1; SMN2 4070/4885SLC22A12 4839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.