Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CFTR | P13569 | 3/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958770 | 0.82 | CFTR (0.37) | TRPV1PTGS2CFTRSCN9APTGS1 | |
| SCHEMBL25686557 | 0.82 | CFTR (0.37) | TRPV1PTGS2CFTRSCN9APTGS1 | |
| SCHEMBL23958851 | 0.82 | CFTR (0.37) | TRPV1PTGS2CFTRSCN9APTGS1 | |
| SCHEMBL30007267 | 0.80 | PTGS2 (0.38) | PTGS2SCN9AKITPTGS1 | |
| SCHEMBL23958629 | 0.80 | PTGS2 (0.38) | PTGS2SCN9AKITPTGS1 | |
| SCHEMBL23958600 | 0.75 | CFTR (0.36) | TRPV1PTGS2MAPK14CYP3A4CFTR | |
| SCHEMBL28909197 | 0.75 | CFTR (0.36) | PTGS2MAPK14CFTRSCN9APTGS1 | |
| SCHEMBL23958691 | 0.75 | CFTR (0.38) | TRPV1PTGS2MAPK14CFTRSCN9A | |
| SCHEMBL23958852 | 0.74 | CFTR (0.35) | TRPV1PTGS2MAPK14CYP3A4CFTR | |
| SCHEMBL23958624 | 0.72 | PTGS2 (0.36) | PTGS2MAPK14SCN9AKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461336-A | RSV inhibiting 3-substituted quinoline and cinnoline derivatives | 爱尔兰詹森科学公司 | 2022-12-09 | — | — | CN | disclosed |