Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.34 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28518833 | 0.84 | RORC (0.44) | RORCCNR1HIF1AKDM4E | |
| SCHEMBL28511837 | 0.84 | RORC (0.44) | RORCCNR1HIF1AKDM4E | |
| SCHEMBL22372103 | 0.82 | HIF1A (0.48) | CNR1HIF1AMAPK14KDM4EALDH1A1 | |
| SCHEMBL28909407 | 0.82 | CA2 (0.41) | RORCCNR1HIF1AKDM4EALDH1A1 | |
| SCHEMBL5592949 | 0.76 | HDAC6 (0.50) | CNR1GSK3B | |
| SCHEMBL19268285 | 0.69 | SCN9A (0.32) | — | |
| SCHEMBL169064 | 0.66 | — | — | |
| SCHEMBL3144624 | 0.65 | CNR1 (0.41) | CNR1KDM4E | |
| SCHEMBL28512245 | 0.65 | RORC (0.46) | RORC | |
| SCHEMBL28511146 | 0.65 | RORC (0.46) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112292373-A | Pyridylpyrazoles as modulators of ROR γ t | 詹森药业有限公司 | 2021-01-29 | — | — | CN | disclosed |