SCHEMBL28909718

SCHEMBL28909718

O=C(S)Cc1cccc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 5/20 0.51
KMT2A Q03164 1/20 0.46
PDCD1 Q15116 1/20 0.43
CD274 Q9NZQ7 1/20 0.43
HNF4A P41235 1/20 0.43
PTGER1 P34995 2/20 0.41
PTGER4 P35408 2/20 0.41
PTGER3 P43115 2/20 0.41
PTGER2 P43116 2/20 0.41
DPP4 P27487 1/20 0.40
LMNA P02545 1/20 0.40
RAB9A P51151 1/20 0.40
HDAC4 P56524 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
CHRNB2 P17787 1/20 0.38
CHRNA4 P43681 1/20 0.38
BCAT2 O15382 1/20 0.38
PTGS1 P23219 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2925420 0.86 AKR1B1 (0.52) FOLH1KMT2APDCD1CD274HNF4A
SCHEMBL9271885 0.85 FOLH1 (0.57) FOLH1KMT2APDCD1CD274PTGER1
SCHEMBL3828115 0.79 PDCD1 (0.50) FOLH1KMT2APDCD1CD274HNF4A
Bicarbonate SCHEMBL17472966 0.79 PDCD1 (0.50) FOLH1KMT2APDCD1CD274HNF4A
SCHEMBL10701580 0.78 FABP4 (0.48) KMT2ARAB9AL3MBTL1
SCHEMBL7204765 0.77 PDCD1 (0.62) FOLH1KMT2APDCD1CD274HNF4A
SCHEMBL5010172 0.77 PDCD1 (0.44) FOLH1KMT2APDCD1CD274HNF4A
SCHEMBL5011002 0.76 PDCD1 (0.43) FOLH1KMT2APDCD1CD274HNF4A
SCHEMBL6701461 0.76 DPP4 (0.47) FOLH1KMT2APDCD1CD274HNF4A
SCHEMBL8459429 0.76 PDCD1 (0.50) FOLH1KMT2APDCD1CD274HNF4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108241257-B Chemically amplified positive photosensitive resin composition, method for producing substrate with mold, and method for producing molded article by plating 奇美实业股份有限公司 2022-11-08 CN disclosed
CN-104102091-B Composition for forming transparent insulating film 东京应化工业株式会社 2020-04-21 CN disclosed