SCHEMBL7204765

SCHEMBL7204765

OCc1cccc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.62
CD274 Q9NZQ7 1/20 0.62
DPP4 P27487 1/20 0.48
PDK2 Q15119 1/20 0.46
KMT2A Q03164 1/20 0.46
FOLH1 Q04609 1/20 0.43
ALDH1A1 P00352 3/20 0.43
HSD17B10 Q99714 2/20 0.43
HPGD P15428 1/20 0.43
BCL2L1 Q07817 1/20 0.43
HNF4A P41235 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
CHRNB2 P17787 1/20 0.41
CHRNA4 P43681 1/20 0.41
APOBEC3G Q9HC16 1/20 0.40
PTGER1 P34995 1/20 0.40
PTGER4 P35408 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5139126 0.84 DPP4 (0.50) PDCD1CD274DPP4KMT2AFOLH1
SCHEMBL11134952 0.84 PDCD1 (0.50) PDCD1CD274DPP4PDK2KMT2A
SCHEMBL11494835 0.83 MMP3 (0.49) PDCD1CD274PDK2KMT2AALDH1A1
SCHEMBL8889986 0.83 PDCD1 (0.62) PDCD1CD274DPP4PDK2KMT2A
SCHEMBL10966421 0.82 KCNA5 (0.54) PDCD1CD274PDK2KMT2AALDH1A1
SCHEMBL2492790 0.82 PDCD1 (0.52) PDCD1CD274PDK2KMT2AENPP1
SCHEMBL2389062 0.82 NR4A2 (0.44) PDCD1CD274PDK2
SCHEMBL1443992 0.82 PDCD1 (0.43) PDCD1CD274PDK2ENPP1
SCHEMBL117091 0.81 PDCD1 (0.65) PDCD1CD274DPP4PDK2KMT2A
SCHEMBL1930918 0.81 PDCD1 (0.48) PDCD1CD274DPP4KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6606138-B2 Liquid crystal layer including a dichroic dye SEIKO EPSON CORPORATION (JP) 2003-08-12 US disclosed
US-20020005930-A1 A LIQUID CRYSTAL LAYER INCLUDING A DICHROIC DYE SEIKO EPSON CORPORATION (JP) 2002-01-17 US disclosed
US-4118487-A ANTIMICROBIAL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1978-10-03 US disclosed