Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | HNF4A | P41235 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010156 | 0.86 | CHRNB2 (0.52) | PDCD1CD274HNF4AKMT2ACHRNB2 | |
| SCHEMBL5010172 | 0.84 | PDCD1 (0.44) | PDCD1CD274HNF4ADPP4KMT2A | |
| SCHEMBL5008840 | 0.84 | HNF4A (0.44) | PDCD1CD274HNF4AKMT2ACHRNB2 | |
| SCHEMBL3828115 | 0.79 | PDCD1 (0.50) | PDCD1CD274HNF4ADPP4KMT2A | |
| SCHEMBL2925420 | 0.79 | AKR1B1 (0.52) | PDCD1CD274HNF4ADPP4KMT2A | |
| SCHEMBL5008897 | 0.79 | HNF4A (0.46) | PDCD1CD274HNF4AKMT2ACHRNB2 | |
| SCHEMBL5012405 | 0.78 | DPP4 (0.50) | PDCD1CD274HNF4ADPP4KMT2A | |
| SCHEMBL7204765 | 0.77 | PDCD1 (0.62) | PDCD1CD274HNF4ADPP4KMT2A | |
| SCHEMBL5008902 | 0.76 | HNF4A (0.43) | PDCD1CD274HNF4AKMT2ACHRNB2 | |
| SCHEMBL28909718 | 0.76 | FOLH1 (0.51) | PDCD1CD274HNF4ADPP4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207864-A1 | Organosilanes, Process For Production of the Same, and Use Thereof | SHARP KABUSHIKI KAISHA (JP) | 2008-08-28 | — | — | US | disclosed |