Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 6/20 | 0.56 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 5/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 9/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30042075 | 0.89 | MAP1LC3B (0.53) | MAP1LC3BCRBN | |
| SCHEMBL28909808 | 0.89 | MAP1LC3B (0.53) | MAP1LC3BCRBN | |
| SCHEMBL23120514 | 0.88 | CRBN (0.52) | MAP1LC3BBRD4CRBN | |
| SCHEMBL25539454 | 0.87 | MAP1LC3B (0.59) | MAP1LC3BBRD4CRBN | |
| SCHEMBL30169800 | 0.87 | CRBN (0.55) | MAP1LC3BBRD4CRBN | |
| SCHEMBL28428885 | 0.86 | MAP1LC3B (0.57) | MAP1LC3BPTK2BRD4EGFRCRBN | |
| SCHEMBL29091122 | 0.86 | CRBN (0.54) | MAP1LC3BBRD4CRBN | |
| SCHEMBL29091179 | 0.86 | CRBN (0.54) | MAP1LC3BBRD4CRBN | |
| SCHEMBL30595224 | 0.86 | CRBN (0.54) | MAP1LC3BBRD4CRBN | |
| SCHEMBL30575188 | 0.86 | CRBN (0.54) | MAP1LC3BBRD4CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214227-A | Heterocyclic compound and application thereof | 上海青玄生物科技有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-111285849-A | Compound for targeted degradation of ALK, c-Met and ROS1 proteins and preparation method thereof | 上海青东生物科技有限公司 | 2020-06-16 | — | — | CN | disclosed |