Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MITF | O75030 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28910016 | 0.82 | CASP3 (0.45) | KDM4EALDH1A1CYP1A2GAAPKM | |
| SCHEMBL1914529 | 0.81 | CYP1A2 (0.63) | L3MBTL1KDM4EALDH1A1CYP1A2HTT | |
| SCHEMBL29935705 | 0.81 | CYP1A2 (0.63) | L3MBTL1KDM4EALDH1A1CYP1A2HTT | |
| SCHEMBL3531515 | 0.80 | LMNA (0.66) | LMNAL3MBTL1KDM4EALDH1A1ELANE | |
| SCHEMBL28910000 | 0.80 | POLB (0.61) | LMNAKDM4EALDH1A1KMT2APKM | |
| SCHEMBL24956766 | 0.74 | HTR1A (0.51) | LMNAL3MBTL1KDM4EALDH1A1ELANE | |
| SCHEMBL3529285 | 0.74 | KMT2A (0.49) | LMNAL3MBTL1KDM4EALDH1A1ELANE | |
| SCHEMBL13701566 | 0.74 | LMNA (0.58) | LMNAL3MBTL1KDM4EALDH1A1ELANE | |
| SCHEMBL24368914 | 0.74 | LMNA (0.58) | LMNAL3MBTL1KDM4EALDH1A1ELANE | |
| SCHEMBL3760247 | 0.73 | LMNA (0.61) | LMNAL3MBTL1KDM4EALDH1A1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335378-A | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2022-11-11 | — | — | CN | disclosed |