Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 3/20 | 0.42 |
| ▸ | ATP4B | P51164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 3/20 | 0.39 |
| ▸ | LITAF | Q99732 | 3/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30251277 | 1.00 | ATP4A (0.42) | ATP4AATP4BALDH1A1SLC6A3HTR1A | |
| SCHEMBL30251377 | 0.80 | PARP1 (0.41) | ALDH1A1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL28910021 | 0.80 | PARP1 (0.41) | ALDH1A1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL24008926 | 0.77 | KDM4E (0.48) | ATP4AATP4BALDH1A1SLC6A3HTR1A | |
| SCHEMBL23858343 | 0.77 | CA12 (0.53) | HPGDSMAPT | |
| SCHEMBL29254511 | 0.73 | KDM4E (0.48) | ALDH1A1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL305745 | 0.72 | ERN1 (0.47) | ALDH1A1 | |
| SCHEMBL15413980 | 0.72 | ALDH1A1 (0.42) | ALDH1A1MAPT | |
| SCHEMBL1335770 | 0.71 | CCR1 (0.58) | ALDH1A1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL20562170 | 0.69 | ALDH1A1 (0.49) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335378-A | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2022-11-11 | — | — | CN | disclosed |