Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28910021 | 1.00 | PARP1 (0.41) | PARP1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL28910004 | 0.80 | ATP4A (0.42) | HTR1AADRA1DADRA1AADRA1BTNKS | |
| SCHEMBL30251277 | 0.80 | ATP4A (0.42) | HTR1AADRA1DADRA1AADRA1BTNKS | |
| SCHEMBL23858857 | 0.73 | GAA (0.43) | PARP1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL15473176 | 0.70 | HPGDS (0.39) | PARP1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3271795 | 0.69 | ERN1 (0.40) | MEN1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL1663012 | 0.69 | ACHE (0.48) | MEN1KMT2ASMN1; SMN2TRIM24TRIM33 | |
| SCHEMBL31227003 | 0.69 | ACHE (0.48) | MEN1KMT2ASMN1; SMN2TRIM24TRIM33 | |
| SCHEMBL13271201 | 0.69 | ERN1 (0.55) | PARP1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14596484 | 0.68 | HTR1A (0.56) | PARP1MEN1KMT2ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126860-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | Janssen Pharmaceutica NV (BE) | 2023-02-08 | — | — | EP | claimed |