Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.38 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.38 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL738661 | 0.83 | CRBN (0.42) | CRBNNPC1RAB9ASRD5A2SSTR5 | |
| SCHEMBL738664 | 0.82 | RXRA (0.43) | CRBNALDH1A1RAB9AL3MBTL1SSTR5 | |
| SCHEMBL28910277 | 0.82 | CYP2A6 (0.39) | ALDH1A1SMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL28910319 | 0.81 | CRBN (0.42) | CRBNALDH1A1NPC1RAB9ASSTR5 | |
| SCHEMBL29538821 | 0.80 | NPC1 (0.51) | ALDH1A1SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL28910279 | 0.80 | CRBN (0.37) | CRBNALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3123277 | 0.77 | HTT (0.43) | SMN1; SMN2NPC1RAB9AL3MBTL1NLRP3 | |
| SCHEMBL28971302 | 0.76 | KDM4E (0.38) | ALDH1A1SMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL24234448 | 0.76 | RXRB (0.41) | CRBNNLRP3HTTSSTR5RXRA | |
| SCHEMBL22805530 | 0.76 | CRBN (0.50) | CRBNSMN1; SMN2NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114394963-B | Isoxazoline compound, preparation method and application | 西北农林科技大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-114394963-A | Isoxazoline compound, preparation method and application | 西北农林科技大学 | 2022-04-26 | — | — | CN | disclosed |