Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL738699 | 0.99 | RXRA (0.43) | RXRARXRBCRBNSSTR5PDK2 | |
| SCHEMBL738698 | 0.91 | KMT2A (0.34) | RXRARXRBCRBNSSTR5RECQL | |
| SCHEMBL20492194 | 0.90 | SSTR5 (0.40) | CRBNSSTR5PDK2MEN1KMT2A | |
| SCHEMBL740580 | 0.87 | KDM4E (0.48) | PDK2MEN1KMT2AL3MBTL1CA1 | |
| SCHEMBL19775268 | 0.87 | KDM4E (0.34) | CRBNRECQLMEN1KMT2AL3MBTL1 | |
| SCHEMBL16274185 | 0.86 | RECQL (0.43) | RECQLMEN1KMT2APDE3AL3MBTL1 | |
| SCHEMBL738661 | 0.86 | CRBN (0.42) | RXRARXRBCRBNSSTR5PDK2 | |
| SCHEMBL2014009 | 0.86 | RXRB (0.41) | RXRARXRBCRBNPDK2RECQL | |
| SCHEMBL12274098 | 0.86 | RXRB (0.41) | RXRARXRBCRBNPDK2RECQL | |
| SCHEMBL29385555 | 0.86 | RXRB (0.41) | RXRARXRBCRBNPDK2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539180-B | Bisamide compound containing isoxazoline and preparation method and application thereof | 贵州大学 | 2025-02-07 | — | — | CN | disclosed |
| CN-118084890-A | Isoxazoline-containing pyrazole amide compound as well as preparation method and application thereof | 安徽农业大学 | 2024-05-28 | — | — | CN | disclosed |
| US-20230355590-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL CORPORATION (JP) | 2023-11-09 | — | — | US | disclosed |
| EP-4021897-A1 | ISOXAZOLINE COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS | PI Industries Ltd. (IN) | 2022-07-06 | — | — | EP | disclosed |
| US-11357231-B2 | Insecticidal compounds based on isoxazoline derivatives | SYNGENTA CROP PROTECTION LLC (US) | 2022-06-14 | — | — | US | disclosed |
| US-11357231-B2 | Insecticidal compounds based on isoxazoline derivatives | SYNGENTA CROP PROTECTION LLC (US) | 2022-06-14 | — | — | US | disclosed |
| CN-114539180-A | Isoxazoline-containing bisamide compound and preparation method and application thereof | 贵州大学 | 2022-05-27 | — | — | CN | disclosed |
| US-10874645-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL CORPORATION (JP) | 2020-12-29 | — | — | US | disclosed |
| US-20200383330-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2020-12-10 | — | — | US | disclosed |
| US-20200383330-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2020-12-10 | — | — | US | disclosed |
| EP-2254863-A1 | PESTICIDAL CONDENSED - RING ARYL COMPOUNDS | Bayer CropScience AG (DE) | 2010-12-01 | — | — | EP | disclosed |
| US-20100137612-A1 | METHOD FOR PRODUCTION OF 3-HYDROXYPROPAN-1-ONE COMPOUND FOR PRODUCTION OF 2- PROPEN-1-ONE COMPOUND AND METHOD FOR PRODUCTION OF ISOXAZLINE COMPOUND | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-06-03 | — | — | US | disclosed |
| EP-1997813-B1 | SUBSTITUTED ISOXAZOLINE COMPOUND AND PEST CONTROL AGENT | NISSAN CHEMICAL IND LTD (JP) | 2010-05-05 | — | — | EP | disclosed |
| EP-2172462-A1 | METHOD FOR PRODUCTION OF 3-HYDROXYPROPAN-1-ONE COMPOUND, METHOD FOR PRODUCTION OF 2-PROPEN-1-ONE COMPOUND, AND METHOD FOR PRODUCTION OF ISOXAZOLINE COMPOUND | Nissan Chemical Industries, Ltd. (JP) | 2010-04-07 | — | — | EP | disclosed |
| US-7662972-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-02-16 | — | — | US | disclosed |
| US-20090312330-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-12-17 | — | — | US | disclosed |
| WO-2009112275-A1 | PESTICIDAL CONDENSED - RING ARYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2009-09-17 | — | — | WO | disclosed |
| EP-1997813-A1 | SUBSTITUTED ISOXAZOLINE COMPOUND AND PEST CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2008-12-03 | — | — | EP | disclosed |
| US-20070066617-A1 | Insecticidal and acaricidal activity for many agricultural insect pests, spider mites; endo- or ecto-parasiticide for mammals or birds; veterinary medicine; environmentally friendly | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-03-22 | — | — | US | disclosed |
| EP-1731512-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2006-12-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137612-A1 | METHOD FOR PRODUCTION OF 3-HYDROXYPROPAN-1-ONE COMPOUND FOR PRODUCTION OF 2- PROPEN-1-ONE COMPOUND AND METHOD FOR PRODUCTION OF ISOXAZLINE COMPOUND | ADH1C, CYP2E1, ADH1A | RXRA 1824/4885RXRB 2042/4885CRBN 3791/4885 |
| US-20230355590-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | HDAC7, ACHE, BRDT | RXRA 952/4885RXRB 1303/4885CRBN 4334/4885 |
| US-20200383330-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | CYP4X1, NPY4R, CASP3 | RXRA 889/4885RXRB 994/4885CRBN 4622/4885 |
| US-20090312330-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | ATM, CHRM1, NAT1 | RXRA 766/4885RXRB 1458/4885CRBN 1852/4885 |
| US-10874645-B2 | Isoxazoline-substituted benzamide compound and pesticide | C3AR1, C5, C9 | RXRA 1346/4885RXRB 926/4885CRBN 1486/4885 |
| US-11357231-B2 | Insecticidal compounds based on isoxazoline derivatives | CYP4X1, NPY4R, CASP3 | RXRA 889/4885RXRB 994/4885CRBN 4622/4885 |
| US-20070066617-A1 | Insecticidal and acaricidal activity for many agricultural insect pests, spider mites; endo- or ecto-parasiticide for mammals or birds; veterinary medicine; environmentally friendly | CHRM1, DDT, ATM | RXRA 841/4885RXRB 1129/4885CRBN 3271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.