Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28910297 | 0.77 | FABP4 (0.40) | CYP2A6ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL31210071 | 0.75 | ADRA2A (0.36) | ADRA2AADRA2BADRA2CCYP2A6ALDH1A1 | |
| SCHEMBL30109166 | 0.71 | MEN1 (0.41) | ADRA2AADRA2BADRA2CCYP2A6ALDH1A1 | |
| SCHEMBL436336 | 0.71 | MEN1 (0.41) | ADRA2AADRA2BADRA2CCYP2A6ALDH1A1 | |
| SCHEMBL24701710 | 0.69 | ADRA2A (0.39) | ADRA2AADRA2BADRA2CCYP2A6ALDH1A1 | |
| SCHEMBL28016128 | 0.69 | ADRA2A (0.39) | ADRA2AADRA2BADRA2CCYP2A6ALDH1A1 | |
| SCHEMBL15241791 | 0.69 | ADRA2A (0.39) | ADRA2AADRA2BADRA2CCYP2A6ALDH1A1 | |
| SCHEMBL28018765 | 0.69 | ADRA2A (0.39) | ADRA2AADRA2BADRA2CCYP2A6ALDH1A1 | |
| SCHEMBL28910308 | 0.69 | HTR2A (0.44) | CYP2A6ALDH1A1CYP1A2TSHRP2RX7 | |
| SCHEMBL4048895 | 0.68 | NOTUM (0.42) | ADRA2AADRA2BADRA2CALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114394963-B | Isoxazoline compound, preparation method and application | 西北农林科技大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-114394963-A | Isoxazoline compound, preparation method and application | 西北农林科技大学 | 2022-04-26 | — | — | CN | disclosed |