Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 11/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | GRK2 | P25098 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30526073 | 0.89 | SDHB (0.37) | SDHBMKNK1MKNK2GRK2P2RX7 | |
| SCHEMBL20985672 | 0.89 | SDHB (0.37) | SDHBMKNK1MKNK2GRK2P2RX7 | |
| SCHEMBL23897426 | 0.89 | SDHB (0.37) | SDHBMKNK1MKNK2GRK2P2RX7 | |
| SCHEMBL20985699 | 0.84 | SDHB (0.36) | SDHBGRK2P2RX7ROCK2 | |
| SCHEMBL20985623 | 0.82 | SDHB (0.46) | SDHBGRK2ROCK2 | |
| SCHEMBL29976336 | 0.82 | SDHB (0.46) | SDHBGRK2ROCK2 | |
| SCHEMBL28307428 | 0.81 | DRD4 (0.30) | — | |
| SCHEMBL20985723 | 0.80 | SDHB (0.45) | SDHB | |
| SCHEMBL20985670 | 0.77 | SDHB (0.48) | SDHBROCK2 | |
| SCHEMBL20985681 | 0.75 | SDHB (0.54) | SDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |