Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 12/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | GRK2 | P25098 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DBH | P09172 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20985623 | 1.00 | SDHB (0.46) | SDHBROCK2GRK2TP53MAPT | |
| SCHEMBL29975895 | 0.93 | SDHB (0.54) | SDHBTP53MAPT | |
| SCHEMBL20985681 | 0.93 | SDHB (0.54) | SDHBTP53MAPT | |
| SCHEMBL20985644 | 0.90 | SDHB (0.51) | SDHB | |
| SCHEMBL30526081 | 0.90 | SDHB (0.51) | SDHB | |
| SCHEMBL26313233 | 0.85 | SDHB (0.49) | SDHBROCK2GRK2TP53MAPT | |
| SCHEMBL26313133 | 0.84 | SDHB (0.47) | SDHBROCK2GRK2TP53MAPT | |
| SCHEMBL20985679 | 0.83 | SDHB (0.64) | SDHBALDH1A1 | |
| SCHEMBL28910483 | 0.82 | SDHB (0.38) | SDHBROCK2GRK2 | |
| SCHEMBL23897426 | 0.81 | SDHB (0.37) | SDHBROCK2GRK2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11725000-B2 | Apoptosis inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2023-08-15 | — | — | US | disclosed |
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11725000-B2 | Apoptosis inhibitors | BAX, SDHA, SDHB | SDHB 3/4885ROCK2 3715/4885GRK2 3248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.